After Hours

Daily exposure to stressors, environmental damage, and internal imbalances can leave skin depleted and vulnerable, especially as you age.

Meanwhile, at night, your skin shifts into repair mode — a natural window of opportunity when cellular renewal peaks and regeneration accelerates. If your nighttime routine isn’t actively supporting this process, you’re missing a critical moment to help your skin recover, strengthen, and reset.

This product is a part of the Plexus® Skin Health Combo.

Product At A Glance

Use With Other Plexus Products: After Hours is designed to work seamlessly with all Plexus Skin Health Combo products – as well as our Skin Health Line add-ons – and is compatible with all Plexus products.

How To Use: Gently massage two pumps onto the face and neck as the last step in your nighttime skincare routine.

Pro Tip: Give it time! Allow the cream to absorb for 15 minutes before heading to bed, ensuring the powerful ingredients stay on your skin instead of transferring to your pillowcase.

Best Time To Use: Evening.

Dermatologist tested, non-comedogenic, cruelty-free*, non-GMO, hypoallergenic, and free from fragrances, harsh surfactants, phthalates, parabens, and other potentially irritating ingredients, including SLS and SLES.

*Finished product not tested on animals.

Available Markets: Canada, United States, Australia (Not for Resale), and New Zealand (Not for Resale).

Who should use After Hours

After Hours is for anyone looking to strengthen their skin’s moisture barrier, support collagen, and enhance cellular renewal. This restorative night cream harnesses ceramides, gentle retinol alternative bakuchiol, and ATP-boosting bioactive ingredients to revive tired-looking skin while soothing irritation and reducing the appearance of redness.

After Hours is ideal for visibly diminishing fine lines and wrinkles, refining surface texture, and minimizing the appearance of pores to wake up to a brighter, more supple, radiant complexion. Simultaneously, multi-dimensional moisture technology brings optimal hydration overnight — when regenerative processes accelerate — for beauty sleep, perfected.

Did you know?

Facial skin has its own circadian rhythm. At night, it shifts into repair mode — which is why overnight products matter.1
Lack of sleep can increase cortisol levels, which break down collagen. That’s why tired skin often looks dull, puffy, and less firm.2
Skin permeability increases at night, which can enhance absorption of topical treatments, making nighttime ideal for applying actives that support repair.3
Transepidermal water loss increases overnight. This makes replenishing hydration and supporting the barrier especially important in evening routines.4

Sources:

1. Andersen B, Duan J, Karri SS. How and Why the Circadian Clock Regulates Proliferation of Adult Epithelial Stem Cells. Stem Cells. 2023 Apr 25;41(4):319-327. doi: 10.1093/stmcls sxad013. PMID: 36740940; PMCID: PMC10128966.
2. WebMD. Published 2014.
3. Levin J, Maibach H. Human skin buffering capacity: an overview. Skin Res Technol. 2008 May;14(2):121-6. doi: 10.1111/j.1600-0846.2007.00271.x. PMID: 18412552.
4. Yosipovitch G, Xiong GL, Haus E, Sackett-Lundeen L, Ashkenazi I, Maibach HI. Time-dependent variations of the skin barrier function in humans: transepidermal water loss, stratum corneum hydration, skin surface pH, and skin temperature. J Invest Dermatol. 1998 Jan;110(1):20-3. doi: 10.1046/j.1523-1747.1998.00069.x. PMID: 9424081.

Key Benefits, Features, and Ingredients

Key Benefits

Fortifies and repairs skin's protective barrier to prevent moisture loss and combat dryness.
Soothes and calms dry, irritated skin while reducing the appearance of redness.
Defends against the visibly damaging effects of environmental stressors through powerful antioxidant protection.
Enhances natural cell renewal for rejuvenated, revitalized skin appearance.
Smooths and evens skin tone and texture while refining the look of pores.
Noticeably diminishes fine lines and wrinkles gently — unlike harsh treatments that damage skin's protective barrier while chasing results.
Supports collagen for visibly improved firmness, elasticity, and bounce.
Helps revitalize the look of tired, stressed skin by encouraging renewal and boosting cellular energy (ATP) for a noticeably refreshed complexion.
Optimizes overnight hydration through multi-dimensional moisture technology.
Complements skin's natural repair processes for a firmer, brighter-looking morning complexion.

Key Features

Powered by gently smoothing bakuchiol and succinic acid to energize skin, these two ingredients support collagen for a firmer appearance and to visibly reduce the look of fine lines — all without the irritation that comes with traditional retinols.
Hydrolyzed yeast protein, panthenol, and ceramides work to restore skin’s moisture barrier, lock in hydration, and soothe dry, irritated skin for a soft, supple feel.
A specialized moisture-replenishing complex of hyaluronic acid, niacinamide, and
glycerin helps visibly improve skin plumpness, strength, and bounce.
Defends against the visibly damaging effects of environmental stressors and oxidative damage, revitalizing the look of stressed or sleep-deprived skin.
Kind-to-Biome certified formula undergoes rigorous testing to maintain healthy skin microbiome balance — supporting beneficial bacteria, discouraging problematic microbes, and preserving essential microbial diversity.
Dermatologist tested for gentleness and suitable for all skin types.
Non-comedogenic formula doesn't clog pores for clear, breathable skin.
Cruelty-free*, non-GMO, hypoallergenic, and free from fragrances, harsh surfactants, phthalates, parabens, and other potentially irritating ingredients, including SLS and SLES.
*Finished product not tested on animals.

Key Ingredients

Advanced antioxidants: A stable vitamin C derivative, tetrahexyldecyl ascorbate, combines with vitamin E to provide powerful antioxidant protection to defend skin against the visibly damaging effects of environmental stressors.
Bakuchiol: A plant-based alternative to retinol that visibly smooths skin texture and promotes renewal without causing irritation.
Hydrolyzed yeast protein: A bioactive ingredient that supports the skin's microbiome by helping nurture beneficial bacteria. By promoting a balanced microbiome, it reinforces the skin's natural defenses, contributing to a healthier, more resilient-looking complexion.
Multi-dimensional hyaluronic acid complex: Immediate plumping and long-lasting hydration are delivered through four forms of hyaluronic acid — Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, and Sodium Hyaluronate Crosspolymer — each working at different depths within the skin.
Niacinamide: A multitasking form of vitamin B3 that helps improve skin clarity and texture. It supports a more even-toned complexion, refines the look of pores, and enhances overall smoothness for healthier-looking skin.
Squalane: A lightweight, skin-friendly emollient that mimics the skin's natural oils, helping to deliver deep lasting hydration. It supports moisture retention, leaving skin to appear soft, smooth, and balanced without a greasy feel.
Succinic acid: A naturally occurring compound that supports skin's energy processes to help revitalize its appearance, promoting a radiant, resilient, and healthy-looking complexion.
Triple ceramide technology: A sophisticated blend of ceramides (NP, AP, and EOP), combined with cholesterol and phytosphingosine, helps strengthen and restore the skin's natural moisture barrier overnight.

Using After Hours

Here are some commonly asked questions about how best to use and experience After Hours.

Question	Answer
Is After Hours suitable for all skin types?	Yes! Our formulations are designed to be gentle, effective, and non-irritating for all skin types.
How do I apply After Hours?	Gently massage two pumps onto the face and neck as the last step in your nighttime skincare routine.
Should I use After Hours right before bed?	Give it time. Allow the cream to absorb for 15 minutes before heading to bed, ensuring the powerful ingredients stay on your skin instead of transferring to your pillowcase.
Can I use After Hours every night?	Yes, it’s gentle and supportive enough for nightly use as part of your regular routine.
Can I use After Hours with my other Plexus products?	Yes! After Hours is designed to work seamlessly with the rest of the Plexus Skin Health Products, as well as our Skin Health Line add-ons, and is compatible with all Plexus products.
Can I use After Hours with my medication?	After Hours is formulated to support overnight renewal in your skin — but it’s always a good idea to speak with your healthcare provider or pharmacist before introducing new skincare products. They can help ensure the products are a good fit for your unique needs and any treatments you're currently using.

About the Formula

Here are some commonly asked questions about the formula for After Hours.

Question	Answer
Does this replace a moisturizer?	Yes, After Hours is designed to nourish the skin with deeper overnight support than a typical moisturizer.
Will it make my skin feel greasy or heavy overnight?	No, After Hours is formulated to deliver rich hydration with a breathable, comfortable finish that won’t clog pores.
How should I store After Hours?	Keep in a cool, dry place away from direct sunlight to maintain potency and texture.

Manufacturing, Health, and Ingredients FAQs

The following are frequently asked questions and answers related to manufacturing, health, and ingredients.

When It Comes To:	The Facts Are:
Using beyond the expiration date	Plexus recommends products be used within the expiration date for best efficacy.
Product safety	Plexus meets or exceeds all regulatory standards and guidelines for product safety and efficacy. Plexus also takes great care in the manufacturing process to prevent allergen cross-contamination. View What steps does Plexus take to prevent allergen cross-contamination in the manufacturing process?
Medical concerns	Anyone who has an allergy, injury, illness, or other medical condition should always consult with a physician prior to using Plexus products or starting any skincare regimen. Also consult with your physician if you have questions or concerns with medication interactions. View What if I have a medical, injury, illness, pregnancy, nursing, or allergy concern about a Plexus® product or the ingredients?
Location of lot number	Lot number is located on the bottom of the bottle.
Allergy concerns	After Hours in hypoallergenic, meaning it’s formulated without common allergens; however, individual sensitivities may still occur.
If pregnant or breastfeeding	As with any new skincare product, we recommend consulting with your healthcare provider before starting use during pregnancy or while nursing. They can provide personalized advice to ensure the products are safe for you and your baby.